Unusual pattern in haemoglobin electrophoresis in Croatian population: a case report
نویسندگان
چکیده
Haemoglobinopathies are hereditary disorders of globin chain synthesis and are the most common inherited diseases worldwide. Haemoglobin E is a structural haemoglobin variant characteristic for South East Asian population. We present a rare and unusual finding of haemoglobin E detected in University Hospital Centre Zagreb by capillary zone electrophoresis. Detection of haemoglobin structural variant helped to avoid misdiagnosis of sideropenic anemia and thus potentially harmful therapeutic intervention. In today's European multiethnic population haemoglobinopathies are a public health issue and Croatian laboratory professionals should be aware of a possibility of finding an unusual haemoglobin pattern.
منابع مشابه
Femoral Head Avascular Necrosis in Heterozygous Sickle Haemoglobin, the Role of Parenteral Drug Abuse: A Case Report
Sickle cell trait is a benign haemoglobin disorder which rarely results in disease or complications. A few cases of osteonecrosis have been reported in the literature in parts of the world with advanced health care system. There are various predispositions to developing avascular necrosis in general, while the sickle beta globin gene inheritance is the most efficient factor. Injection drug abus...
متن کاملMesenteric cyst and unusual manifestation: a case report
Introduction: Mesenteric cysts are rare intra abdominal masses and its prevalence is 1 out of 140000 in general hospitals and 1 out of 20000 in pediatric hospitals. In majority of the cases it is benign with several manifestations. Diagnosis is difficult , but with suspicion to cyst and using paraclinical procedures can be led to definite diagnosis. Case report: In this study a mesenteric cys...
متن کاملFirst Case Report of an Unusual Echis genus (Squamata: Ophidia: Viperidae) Body Pattern Design in Iran
Three families of venomous snakes exist in Iran including Viperidae, Elapidae, and Hydrophidae. Viperidae family is the only family with a widespread distribution. Saw-scaled vipers are important poisonous snakes in Asia and Africa. This name is given to this snake due to the presence of obliquely keeled and serrated lateral body scales. Distribution of this genera is mostly reported in t...
متن کاملAn Unusual Form of Tinea Versicolor: A Case Report
Tinea versicolor is caused by Malassezia furfur and presents as hypo or hyper-pigmented coalescing scaly macules on the trunk and upper arms. Sites of predilection are the sternal region and the sides of the chest, the abdomen, back, pubis, neck, and intertriginous areas. We report a case of tinea versicolor with a reticulated pattern on acral sites.
متن کاملUnusual presentation of a patient with hemoglobin Constant Spring and immune hemolytic anemia
Abstract Introduction: Hemoglobin Constant Spring (Hb CS), a abnormal Hb characterized by elongated α-globin chain resulting from mutations of the termination codon in the α2 - globin gene , is the most common nondelitional α-thalassemic mutation and is an important cause of HbH like disease in Southeast Asia. Case Report: A 9- years-old female with immune hemolytic anemia and splenomegally...
متن کامل